Moiz Bushra, Arif Fauzia Muhammad, Hashmi Khalid Zafar
Department of Pathology and Microbiology, Aga Khan University Hospital, Karachi.
J Pak Med Assoc. 2006 Aug;56(8):356-9.
To analyze the current situation of use and misuse of fresh frozen plasma (FFP) in various clinical situations.
This was a cross sectional study done at Liaquat National Hospital (LNH) during a period of 4 months from December 2002 to March 2003. About 300 file records of those patients who received fresh frozen plasma were studied. Each file record was checked for the diagnosis of the patient, coagulation profile and doctor's trigger for blood transfusion. The indications of FFP were checked according to guidelines set by British Committee of Standards and Haematology.
Of 1486 units of FFP that were transfused to 300 patients, it was observed that 78.6% (1169 / 1486) of FFP was appropriately transfused while the remaining 21.3% (317/1486 units) was used without any supportive evidence.
Although majority of the plasma was used appropriately, a considerable volume of plasma was also wasted.
分析新鲜冰冻血浆（FFP）在各种临床情况下的使用和滥用现状。
这是一项于2002年12月至2003年3月期间在利亚卡特国家医院（LNH）进行的为期4个月的横断面研究。研究了约300例接受新鲜冰冻血浆治疗患者的病历记录。检查每份病历记录中患者的诊断、凝血情况以及医生的输血指征。根据英国血液学标准委员会制定的指南检查FFP的适应证。
在输注给300例患者的1486单位FFP中，发现78.6%（1169/1486）的FFP输注恰当，而其余21.3%（317/1486单位）的使用没有任何支持证据。
虽然大部分血浆使用恰当，但仍有相当数量的血浆被浪费。
