Deng Yin-quan, Fan Xiao-fen, Wu Guo-lin
The First Affiliated Hospital of Medical College, Zhejiang University, Hangzhou 310003.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2006 Aug;26(8):706-9.
To observe the effect of Yuquan Pill (YP) on proinflammatory cytokines in patients with type 2 diabetes mellitus (DM2).
Ninety patients with DM2 were randomly divided into the treated group and the control group by the ratio of 2:1. Both groups were treated with Glucobay on the base of dietary and exercise therapy for 3 months, with YP, given to the treated group additionally 6 g four times a day. And the changes of proinflammatory cytokines, including C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), etc. were observed.
The levels of serum CRP,TNF-alpha and IL-6 significantly lowered after treatment in both groups (P<0.01), and the improvement in the treated group was superior to that in the control group (P<0.01).
YP could reduce the levels of the increased proinflammatory cytokines in patients with DM2.
观察玉泉丸（YP）对2型糖尿病（DM2）患者促炎细胞因子的影响。
90例DM2患者按2:1比例随机分为治疗组和对照组。两组均在饮食和运动治疗基础上服用拜糖平3个月，治疗组加用YP，每日4次，每次6 g。观察促炎细胞因子，包括C反应蛋白（CRP）、肿瘤坏死因子-α（TNF-α）和白细胞介素-6（IL-6）等的变化。
两组治疗后血清CRP、TNF-α和IL-6水平均显著降低（P<0.01），且治疗组改善情况优于对照组（P<0.01）。
YP可降低DM2患者升高的促炎细胞因子水平。
