Niedecken H W, Biwer E, Bauer R, Kreysel H W
Universitäts Haut- und Poliklinik, Rheinischen Friedrich-Wilhelm-Universität Bonn.
Z Hautkr. 1990 Jun;65(6):578-81.
Acrosyringium and infundibulum are epidermal structures with different morphology, but functional similarities regarding re-epithelialization, transport of antigens, and attraction of infiltrates. Immunomorphologically, the infundibula revealed an immunoreactivity of Langerhans cells and keratinocytes comparable with that of the interfollicular epidermis, whereas the acrosyringia reacted differently because of the permanent expression of MHC class II antigens and reduced Langerhans cells in the perisyringial region. Our findings suggest that these epidermal compartments differ with regard to their individual immunologic situations. While the mechanisms of epidermal immunity known from the interfollicular epidermis are possibly the same in the infundibula, we have to expect a basically different immunologic situation in the acrosyringia.
顶泌汗腺导管和漏斗部是具有不同形态的表皮结构，但在再上皮化、抗原转运和浸润细胞吸引方面具有功能相似性。免疫形态学上，漏斗部显示出与毛囊间表皮相当的朗格汉斯细胞和角质形成细胞免疫反应性，而顶泌汗腺导管反应不同，因为其MHC II类抗原的持续表达以及顶泌汗腺周围区域朗格汉斯细胞减少。我们的研究结果表明，这些表皮区域在各自的免疫状况方面存在差异。虽然从毛囊间表皮已知的表皮免疫机制在漏斗部可能相同，但我们预计顶泌汗腺导管存在根本不同的免疫状况。
