Scarazatti E, Moscarella V, Garelli G, Melloni G F
Laboratorio Analisi Chimico-Cliniche di Garbagnate, USSL 67.
Boll Soc Ital Biol Sper. 1990 Apr;66(4):381-5.
In this work we have considered CK isoenzymes (CKBB-CKMT) as tumoral markers. The statistical comparison of the results (x2) executed on thirty neoplastic patients selected at random, has proved that CKBB and/or CKMT frequency is the same as the CEA one (CEA vs BB = N.S.; CEA VS MT = N.S.; CEA VS BB + MT = N.S.) and higher than AFP one (AFP VS BB = P less than 0.001; AFP VS MT = P less than 0.01). The isoenzymes' determination was executed by electrophoretic method (Helena) which is sensitive, specific and swift.
在这项研究中，我们将肌酸激酶同工酶（CKBB - CKMT）视为肿瘤标志物。对随机选取的30例肿瘤患者的结果进行统计学比较（x2检验），结果表明CKBB和/或CKMT的出现频率与癌胚抗原（CEA）相同（CEA与BB比较 = 无显著差异；CEA与MT比较 = 无显著差异；CEA与BB + MT比较 = 无显著差异），且高于甲胎蛋白（AFP）（AFP与BB比较 = P < 0.001；AFP与MT比较 = P < 0.01）。同工酶的测定采用电泳法（海伦娜法），该方法灵敏、特异且快速。
