Brooks A M, Gillies W E
Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.
Aust N Z J Ophthalmol. 1990 May;18(2):179-85. doi: 10.1111/j.1442-9071.1990.tb00611.x.
Patients with neovascular glaucoma (NVG) often present with neovascularisation of the iris (NVI) already established and prompt energetic treatment of these patients is needed to reverse or stabilise the condition with possible retention of some visual function. In this series if the ocular media were still clear panretinal photocoagulation (PRP) caused regression of NVI in about 60% of cases and if a persistent rise in intraocular pressure (IOP) were still present this could be dealt with by drainage operation, Molteno implant or cyclophotocoagulation. If the media were already opaque or NVI did not regress then a Molteno implant or cyclophotocoagulation was used to reduce the IOP, preserving corneal endothelial function so that a comfortable eye could be obtained. Some regression of the NVI process was likely with time if the IOP were controlled by surgical treatment. Of 32 patients reviewed here, 20 patients developed NVG following a central retinal vein occlusion; in six patients NVG followed diabetic proliferative retinopathy, in five it followed arterial occlusion, and in one it followed an old traumatic retinal detachment. In those patients where NVG followed venous or arterial occlusion the common risk factors were always present. Patients were usually under treatment for their systemic condition but this treatment should be reviewed.
新生血管性青光眼（NVG）患者通常就诊时虹膜新生血管（NVI）已经形成，需要对这些患者迅速进行积极治疗，以逆转或稳定病情，并尽可能保留一定的视功能。在本系列研究中，如果眼内介质仍清晰，全视网膜光凝（PRP）可使约60%的病例中的NVI消退；如果眼压（IOP）持续升高，则可通过引流手术、莫尔顿植入物或睫状体光凝来处理。如果眼内介质已混浊或NVI未消退，则使用莫尔顿植入物或睫状体光凝来降低眼压，保留角膜内皮功能，从而使眼睛保持舒适。如果通过手术治疗控制眼压，随着时间推移，NVI过程可能会有所消退。在此回顾的32例患者中，20例患者在视网膜中央静脉阻塞后发生NVG；6例患者在糖尿病增殖性视网膜病变后发生NVG，5例在动脉阻塞后发生，1例在陈旧性外伤性视网膜脱离后发生。在那些NVG继发于静脉或动脉阻塞的患者中，常见的危险因素始终存在。患者通常正在接受全身性疾病的治疗，但对此治疗应进行复查。
