Bailenger J, Faraggi G
Ann Parasitol Hum Comp. 1975 Mar-Apr;50(2):187-97. doi: 10.1051/parasite/1975502187.
In order to explain the hypocorticosteronemia which establishes itself in rats with Strongyloides ratti parasites, we are proceeding with a functional exploration of the hypothalamo-hypophyso-corticosurrenal axis in experimentally infested rodents. The adreno-cortico-tropic-hormone test (A.C.T.H.), stress to ether and the Lysin-8-Vasopressin and Metopirone tests lead to concordant results: -- the hypothalamo-pituitary-corticosurrenal present a functional integrity which allows it to react normally to direct stimulation or to feed-back; -- the deficiency seems to relate to the hypothalamic secretion of the cortico-releasing factor; -- the cause would stem from an inhibition of the nervous mechanism which regulates this neurosecretion.
为了解释感染鼠类圆线虫的大鼠体内出现的低皮质醇血症，我们正在对实验性感染的啮齿动物的下丘脑 - 垂体 - 肾上腺轴进行功能探索。促肾上腺皮质激素试验（ACTH）、乙醚应激试验以及赖氨酸 - 8 - 加压素和甲吡酮试验得出了一致的结果：——下丘脑 - 垂体 - 肾上腺轴具有功能完整性，能够对直接刺激或反馈做出正常反应；——这种缺乏似乎与促肾上腺皮质激素释放因子的下丘脑分泌有关；——其原因可能源于调节这种神经分泌的神经机制受到抑制。
