Helson L, Krochmal P, Hajdu S I
Ann Clin Lab Sci. 1975 Jul-Aug;5(4):294-7.
The practical value of cytologic examination in the clinical management of children with cancer was determined by analyzing 2,363 cytologic specimens collected during a two year period. The specimens included cerebrospinal fluid, pleural and peritoneal effusions, urine and tracheal aspirates from 347 children with cancer. Malignant tumor cells were detected in 266 specimens obtained from 106 children with the following malignant neoplasms: leukemia 44/133, malignant lymphoma 13/64, soft tissue sarcoma 13/48, neuroblastoma 13/26, Wilms' tumor 4/18, malignant teratoma 4/13, osteogenic sarcoma 7/11, Ewing's sarcoma 2/10, brain tumor 5/6 and retinoblastoma 1/1. No malignant cells were detected in fluids from 18 patients with other tumors. The malignant cells were identified most ofter in spinal fluid, pleural and peritoneal effusions. Cytologic examination appears to be of value in the clinical management of children with cancer.
通过分析两年期间收集的2363份细胞学标本，确定了细胞学检查在儿童癌症临床管理中的实用价值。这些标本包括来自347名癌症患儿的脑脊液、胸腔和腹腔积液、尿液及气管吸出物。在从106名患有以下恶性肿瘤的儿童获得的266份标本中检测到恶性肿瘤细胞：白血病44/133、恶性淋巴瘤13/64、软组织肉瘤13/48、神经母细胞瘤13/26、肾母细胞瘤4/18、恶性畸胎瘤4/13、骨肉瘤7/11、尤因肉瘤2/10、脑肿瘤5/6和视网膜母细胞瘤1/1。18名患有其他肿瘤的患者的体液中未检测到恶性细胞。恶性细胞最常出现在脑脊液、胸腔和腹腔积液中。细胞学检查在儿童癌症的临床管理中似乎具有价值。
