Geisinger K R, Hajdu S I, Helson L
Acta Cytol. 1984 Jan-Feb;28(1):16-28.
During the last 11 years, 144 nonlymphoreticular neoplasms were diagnosed in exfoliative cytology specimens obtained from patients younger than 17 years of age. Neuroblastoma was the single most common neoplasm (30 cases). Other categories of malignant neoplasms were primary bone tumors (30 cases), soft-tissue sarcomas (25 cases), brain tumors (25 cases) and epithelial neoplasms (7 cases). Of the 780 cytologic specimens, 335 were positive for malignant cells. Serous effusions provided most of the positive specimens from patients with neuroblastoma, germ-cell tumors and bone sarcomas. Exfoliated cells of metastatic embryonal rhabdomyosarcoma and primary brain tumors were detected most often in cerebrospinal fluid specimens. A most unusual presentation of an immature teratoma of the ovary is described in some detail. Despite the rarity of pediatric neoplasms, certain specific or suggestive cytologic features were recognized, including rosette formation of neuroblasts, nuclear notching of myoblasts, pleomorphism of osteoblasts and fibrillar processes of glial elements.
在过去11年中，从17岁以下患者的脱落细胞学标本中诊断出144例非淋巴网状肿瘤。神经母细胞瘤是最常见的单一肿瘤（30例）。其他恶性肿瘤类别包括原发性骨肿瘤（30例）、软组织肉瘤（25例）、脑肿瘤（25例）和上皮性肿瘤（7例）。在780份细胞学标本中，335份恶性细胞呈阳性。浆液性积液提供了神经母细胞瘤、生殖细胞肿瘤和骨肉瘤患者的大部分阳性标本。转移性胚胎性横纹肌肉瘤和原发性脑肿瘤的脱落细胞最常在脑脊液标本中检测到。本文详细描述了一例非常罕见的卵巢未成熟畸胎瘤表现。尽管儿童肿瘤罕见，但仍可识别某些特定或提示性的细胞学特征，包括神经母细胞的菊形团形成、成肌细胞的核切迹、成骨细胞的多形性和神经胶质成分的纤维状突起。
