Batra Yatindra K, Rajeev S
Department of Anaesthesia and Intensive Care Unit, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Paediatr Anaesth. 2006 Oct;16(10):1090-3. doi: 10.1111/j.1460-9592.2006.01944.x.
The antiphospholipid antibody syndrome (or the anticardiolipin antibody syndrome) is characterized by the presence of autoantibodies. Its major association is with systemic lupus erythematosus. 'Catastrophic' antiphospholipid syndrome (CAPS) is defined as an accelerated form of APS usually resulting in multiorgan failure and can be precipitated by surgery. We present the case of a 12-year-old male child who presented for enucleation of his left eye for fungal endopthalmitis. This patient had a history of CAPS 2 months before surgery with myocardial, gastrointestinal, renal and laryngeal involvement that improved on aggressive treatment and was subsequently managed on an outpatient basis for 2 months before presenting for enucleation. To the best of our knowledge, this is the first case of CAPS in a child reported in the anesthetic literature. Further aspects of this puzzling condition and its anesthesia implications are discussed.
抗磷脂抗体综合征（或抗心磷脂抗体综合征）的特征是存在自身抗体。其主要关联疾病是系统性红斑狼疮。“灾难性”抗磷脂综合征（CAPS）被定义为抗磷脂综合征的一种加速形式，通常会导致多器官功能衰竭，且手术可能会诱发该病。我们报告了一例12岁男性儿童的病例，该患儿因真菌性眼内炎接受左眼眼球摘除术。该患者在手术前2个月有CAPS病史，累及心肌、胃肠道、肾脏和喉部，经积极治疗后病情好转，随后在门诊治疗2个月后前来接受眼球摘除术。据我们所知，这是麻醉学文献中报道的首例儿童CAPS病例。本文讨论了这种令人困惑的疾病的其他方面及其麻醉相关问题。
