Jayaraman Anu G, Cassarino David, Advani Ranjana, Kim Youn H, Tsai Eunice, Kohler Sabine
Department of Pathology, Stanford University Medical Center, Stanford, California 94305-5324, USA.
J Cutan Pathol. 2006 Sep;33 Suppl 2:6-11. doi: 10.1111/j.1600-0560.2006.00489.x.
Angioimmunoblastic T-cell lymphoma (AILT) is an aggressive peripheral T-cell lymphoma that is frequently accompanied by a cutaneous eruption. The cutaneous findings most commonly consist of a maculopapular eruption on the trunk. However, purpura, infiltrated or urticarial plaques, papulovesicular lesions, nodules, and erythroderma have also been reported. Histologic findings in the lymph node are characteristic, while those in the skin may show one of four patterns. Here, we review the previously reported histologic patterns and present a case of AILT involving the skin with a unique histologic appearance of necrotizing granulomas with abundant histiocytes and eosinophils, mimicking an infectious etiology.
血管免疫母细胞性T细胞淋巴瘤（AILT）是一种侵袭性外周T细胞淋巴瘤，常伴有皮肤疹。皮肤表现最常见的是躯干上的斑丘疹。然而，紫癜、浸润性或荨麻疹样斑块、丘疹水疱性病变、结节和红皮病也有报道。淋巴结的组织学表现具有特征性，而皮肤的组织学表现可能呈现四种模式之一。在此，我们回顾先前报道的组织学模式，并报告一例累及皮肤的AILT病例，其具有独特的组织学表现，即坏死性肉芽肿伴大量组织细胞和嗜酸性粒细胞，酷似感染性病因。
