在多发性皮肤平滑肌肿瘤背景下发生的伴有黏液样改变的皮肤平滑肌肉瘤。
Cutaneous leiomyosarcoma with myxoid alteration arising in a setting of multiple cutaneous smooth muscle neoplasms.
作者信息
Utikal Jochen, Haus Georg, Poenitz Nina, Koenen Wolfgang, Back Walter, Dippel Edgar, Gratchev Alexei, Goerdt Sergij
机构信息
Department of Dermatology, Venereology and Allergology, University Medical Center Mannheim, Ruprecht-Karl University of Heidelberg, Mannheim, Germany.
出版信息
J Cutan Pathol. 2006 Sep;33 Suppl 2:20-3. doi: 10.1111/j.1600-0560.2006.00491.x.
BACKGROUND
Cutaneous leiomyomas and leiomyosarcomas are rare tumors that originate from the arrector muscle of hair follicles or the smooth muscle of blood vessels.
CASE REPORT
A 74-year-old male presented with a single, erythematous nodule on the left upper arm. This lesion developed within the excision scar of a piloleiomyoma that had been excised 3 years ago. Additionally, physical examination revealed a tender nodule on the right ear.
RESULTS
Histological examination showed a cutaneous leiomyosarcoma with myxoid alteration on the upper arm and an angioleiomyoma on the right ear.
CONCLUSION
Myxoid leiomyosarcomas have exclusively been reported in the uterus and gastrointestinal tract, but not in the skin. Here, we describe a case of cutaneous leiomyosarcoma with myxoid alteration that developed in the excision scar of a piloleiomyoma and was accompanied by a cutaneous angioleiomyoma in a different location.
背景
皮肤平滑肌瘤和平滑肌肉瘤是罕见的肿瘤，起源于毛囊竖毛肌或血管平滑肌。
病例报告
一名74岁男性左上臂出现单个红斑结节。该病变发生在3年前切除的皮肤平滑肌瘤的手术瘢痕内。此外，体格检查发现右耳有一个压痛结节。
结果
组织学检查显示左上臂为伴有黏液样改变的皮肤平滑肌肉瘤，右耳为血管平滑肌瘤。
结论
黏液样平滑肌肉瘤仅在子宫和胃肠道有报道，皮肤未见报道。在此，我们描述了一例发生在皮肤平滑肌瘤切除瘢痕内并伴有另一部位皮肤血管平滑肌瘤的伴有黏液样改变的皮肤平滑肌肉瘤病例。
Zotero 插件