具有假菊形团的脂溢性角化病和釉质样脂溢性角化病：两种新的组织病理学变体。
Seborrheic keratosis with pseudorosettes and adamantinoid seborrheic keratosis: two new histopathologic variants.
作者信息
Requena Luis, Kutzner Heinz
机构信息
Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
出版信息
J Cutan Pathol. 2006 Sep;33 Suppl 2:42-5. doi: 10.1111/j.1600-0560.2006.00528.x.
AIMS
Seborrheic keratoses are the most common benign cutaneous neoplasms in adult and middle-age patients. There are six distinctive histopathologic variants of seborrheic keratosis, namely, acanthotic or solid, reticulated or adenoid, hyperkeratotic or papillomatous, clonal or nested, irritated and inflamed.
METHODS
We report two additional histopathologic variants of seborrheic keratosis.
RESULTS
One lesion showed abundant intercellular mucin, closely resembling to adamantinoma, and therefore was named adamantinoid seborrheic keratosis. The other one exhibited a peculiar distribution of the basaloid keratinocytes, which were arranged radially around small central spaces, resulting in pseudorosette formation.
DISCUSSION
To our knowledge, these two histopathologic variants of seborrheic keratosis have been not previously described in the literature.
目的
脂溢性角化病是成人和中年患者中最常见的良性皮肤肿瘤。脂溢性角化病有六种独特的组织病理学变体，即棘皮瘤型或实性、网状或腺样、角化过度或乳头瘤样、克隆性或巢状、刺激性和炎症性。
方法
我们报告了另外两种脂溢性角化病的组织病理学变体。
结果
一个病变显示细胞间黏液丰富，与成釉细胞瘤非常相似，因此被命名为成釉细胞瘤样脂溢性角化病。另一个表现为基底样角质形成细胞的特殊分布，它们围绕小的中央间隙呈放射状排列，形成假菊形团。
讨论
据我们所知，这两种脂溢性角化病的组织病理学变体以前在文献中尚未被描述。
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