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脂溢性角化病:罕见表现报告及对该问题现有认知的提示

Seborrheic Keratosis: Report of a Rare Presentation and Reminder of the Current Knowledge of the Problem.

作者信息

Lahbacha Bahaeddine, Nechi Salwa, Chaabane Abir, Bani Amina, Kchaou Majdi, Chtourou Fadhel, Mfarrej Mohamed Karim, Douggaz Amel, Chelbi Emna

机构信息

Department of Pathology, Mohamed Taher Maamouri University Hospital, Nabeul, Tunisia.

Department of General Surgery, Mohamed Taher Maamouri University Hospital, Nabeul, Tunisia.

出版信息

Clin Pathol. 2024 May 25;17:2632010X241255874. doi: 10.1177/2632010X241255874. eCollection 2024 Jan-Dec.

DOI:10.1177/2632010X241255874
PMID:38799019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11128169/
Abstract

A 75-year-old man presented with an abdominal enlarging painless tumor of the skin evolving over the last 30 years. His past medical history was unremarkable. Physical examination revealed a brownish pedunculated cutaneous mass which had an irregular keratotic warty surface with no discharge or ulceration. The mass was clinically presumed to be a melanocytic tumor, or a verrucous carcinoma. A monoblock excision of the mass was performed with a good outcome. The specimen was then sent to our pathology department to rule out malignancy. Macroscopic examination revealed a brownish tumor of 7.5 × 7 × 1.5 cm which had fissures and cauliflower-like appearance. Final histological report concluded to a giant seborrheic keratosis.

摘要

一名75岁男性患者,其腹部有一个无痛性且不断增大的皮肤肿物,病程长达30年。他既往病史无特殊。体格检查发现一个带蒂的褐色皮肤肿物,表面有不规则的角化性疣状外观,无分泌物或溃疡。临床上推测该肿物为黑素细胞肿瘤或疣状癌。对肿物进行了整块切除,效果良好。随后将标本送至我们的病理科以排除恶性病变。宏观检查显示一个7.5×7×1.5厘米的褐色肿瘤,有裂隙和菜花状外观。最终组织学报告诊断为巨大脂溢性角化病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9ac/11128169/5f872eb84545/10.1177_2632010X241255874-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9ac/11128169/d3c73ca79ea9/10.1177_2632010X241255874-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9ac/11128169/5f872eb84545/10.1177_2632010X241255874-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9ac/11128169/d3c73ca79ea9/10.1177_2632010X241255874-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d9ac/11128169/5f872eb84545/10.1177_2632010X241255874-fig2.jpg

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J Dtsch Dermatol Ges. 2023 Mar;21(3):265-277. doi: 10.1111/ddg.14984. Epub 2023 Mar 9.
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Update of pathophysiology and treatment options of seborrheic keratosis.脂溢性角化病的病理生理学和治疗选择的更新。
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Seborrheic Keratosis With Sebaceous Differentiation, a Series of 8 Cases and Critical Review of the Literature.脂溢性角化病伴皮脂腺分化,8 例系列病例及文献复习。
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