Gupta Rajesh, Lakhtakia Sandeep, Tandan Manu, Banerjee Rupa, Ramchandani Mohan, Anuradha S, Ramji C, Rao G V, Pradeep R, Reddy D Nageshwar
Department of Medical Gastroenterology, Asian Institute of Gastroenterology, 6-3-661 Somajiguda, Hyderabad 500-082, India.
Indian J Gastroenterol. 2006 Jul-Aug;25(4):188-90.
Obscure gastrointestinal bleeding (OGIB) is a common indication for capsule endoscopy (CE). Reports on diagnostic yield of CE in this situation show a wide variation. We evaluated the diagnostic yield and clinical impact of CE in patients with OGIB.
We reviewed the medical records of patients with OGIB who underwent CE at our institution between June 2002 and October 2005.
154 patients (mean age 47 [SD 17] years; 117 men), including 74 with overt OGIB and 80 with occult OGIB, underwent CE. CE yielded positive findings in 57 of 74 patients (77%) with overt OGIB and 22 of 80 (27%) of those with occult OGIB (p < 0.0001); the overall positive diagnostic yield was 52%. NSAID-induced lesions (15%), angiodysplasias (14%) and aphthous ulcers (12%) were the most frequent findings. CE helped in planning further management in 79% of patients with overt OGIB and 26% of those with occult OGIB.
CE is a useful diagnostic technique in patients with OGIB, especially those with overt OGIB.
不明原因的消化道出血（OGIB）是胶囊内镜检查（CE）的常见适应证。关于这种情况下CE诊断率的报道差异很大。我们评估了CE对OGIB患者的诊断率及临床影响。
我们回顾了2002年6月至2005年10月在我院接受CE检查的OGIB患者的病历。
154例患者（平均年龄47[标准差17]岁；117例男性）接受了CE检查，其中74例为显性OGIB，80例为隐性OGIB。CE在74例显性OGIB患者中的57例（77%）及80例隐性OGIB患者中的22例（27%）发现了阳性结果（p<0.0001）；总体阳性诊断率为52%。非甾体抗炎药引起的病变（15%）、血管发育异常（14%）和阿弗他溃疡（12%）是最常见的发现。CE有助于79%的显性OGIB患者和26%的隐性OGIB患者制定进一步的治疗方案。
CE是OGIB患者，尤其是显性OGIB患者的一种有用的诊断技术。
