Choudry Q, Patel H C, Gurusinghe N T, Evans D G
Department of Neurosurgery, Royal Preston Hospital, Preston, Lancashire, PR2 9HT, UK.
Childs Nerv Syst. 2007 Jan;23(1):133-6. doi: 10.1007/s00381-006-0178-4. Epub 2006 Sep 15.
We report two cases of radiation-induced intracranial tumours after treatment for medulloblastoma presenting in children with nevoid basal cell carcinoma syndrome.
These cases illustrate the need for judicious use of post-operative radiotherapy as secondary tumors are commonly reported. This is particularly important as the initial tumour in this cohort is of the 'less aggressive' desmoplastic subtype.
我们报告了两例患有痣样基底细胞癌综合征的儿童在接受髓母细胞瘤治疗后发生放射性颅内肿瘤的病例。
这些病例表明,由于继发性肿瘤屡有报道,因此需要谨慎使用术后放疗。这一点尤为重要,因为该队列中的初始肿瘤为“侵袭性较小”的促纤维增生型。