相似背景下“reeler”突变两个等位基因的小脑表型。

Cerebellar phenotype of two alleles of the 'reeler' mutation on similar backgrounds.

作者信息

Goffinet A M

机构信息

Department of Physiology, FNPD School of Medicine, Namur, Belgium.

出版信息

Brain Res. 1990 Jun 11;519(1-2):355-7. doi: 10.1016/0006-8993(90)90102-h.

DOI:10.1016/0006-8993(90)90102-h

PMID:1697778

Abstract

Using congenic strains, the two alleles ('Ed' and 'Orl') of the reeler mutation in mice have been compared on two genetic backgrounds (B6 and C). The phenotypic differences in cerebellar organization between the 4 homozygous reeler mutant strains appeared related to the genetic background rather than to allelic differences.

摘要

利用同源近交系，在两种遗传背景（B6和C）下对小鼠里勒突变的两个等位基因（“Ed”和“Orl”）进行了比较。4种纯合里勒突变体品系之间小脑组织的表型差异似乎与遗传背景有关，而非等位基因差异。