Louie Lana D, Crowe Joseph P, Dawson Andrea E, Lee Katherine B, Baynes Deborah L, Dowdy Tami, Kim Julian A
Department of Surgery, The Cleveland Clinic, Cleveland, OH 44106-5047, USA.
Am J Surg. 2006 Oct;192(4):530-3. doi: 10.1016/j.amjsurg.2006.06.004.
The purpose of the current study was to review characteristics of patients with nipple discharge who underwent ductoscopy-assisted excisional biopsy who had a final diagnosis of carcinoma.
A retrospective review was performed of patients presenting with pathologic nipple discharge (PND) who underwent ductoscopy-assisted excisional biopsy and had a final diagnosis of carcinoma.
A total of 14 (7%) of 188 patients who underwent ductoscopy-assisted excision had a final pathology of ductal carcinoma-in-situ (DCIS) (12/14, 86%) or invasive breast cancer with DCIS (2/14, 14%). Duct wall irregularities or intraluminal growths were visualized during ductoscopy in 8 of the 14 (57%) breast cancer patients. There were no visual abnormalities noted during ductoscopy that accurately predicted a final diagnosis of malignancy.
Although occult malignancies can be identified in patients undergoing ductoscopy-assisted biopsy for PND, no clear morphologic changes visualized during ductoscopy definitively indicated the presence of malignancy.
本研究旨在回顾经乳管镜辅助切除活检最终诊断为癌的乳头溢液患者的特征。
对因病理性乳头溢液（PND）接受乳管镜辅助切除活检且最终诊断为癌的患者进行回顾性研究。
188例行乳管镜辅助切除术的患者中，共有14例（7%）最终病理诊断为导管原位癌（DCIS）（12/14，86%）或伴有DCIS的浸润性乳腺癌（2/14，14%）。14例乳腺癌患者中有8例（57%）在乳管镜检查时可见管壁不规则或管腔内肿物。乳管镜检查时未发现能准确预测最终恶性诊断的视觉异常。
尽管在因PND接受乳管镜辅助活检的患者中可发现隐匿性恶性肿瘤，但乳管镜检查时未见明确的形态学改变可确切表明存在恶性肿瘤。
