Schwarz Ernst R, Rastogi Saurabh, Kapur Vishal, Sulemanjee Nasir, Rodriguez Jennifer J
Division of Cardiology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
J Am Coll Cardiol. 2006 Sep 19;48(6):1111-9. doi: 10.1016/j.jacc.2006.05.052. Epub 2006 Aug 28.
Chronic heart failure (HF) and erectile dysfunction (ED) are 2 highly prevalent disorders that frequently occur concomitantly. Coronary artery disease, HF, and ED share several common risk factors, including diabetes mellitus, hypertension, smoking, and dyslipidemia. Additionally, the distinct physiologic sequelae of HF create unique organic and psychologic factors contributing to ED in this patient population. Standard HF therapy with beta-receptor blockers, digoxin and thiazide diuretics may worsen sexual dysfunction owing to medication side effects. This may, in turn, lead to noncompliance in misguided efforts to retain satisfactory sexual activity, with secondary worsening of cardiac capacity. This review describes the unique aspects of ED in the HF population.
慢性心力衰竭（HF）和勃起功能障碍（ED）是两种高度常见且常同时发生的疾病。冠状动脉疾病、HF和ED有几个共同的危险因素，包括糖尿病、高血压、吸烟和血脂异常。此外，HF独特的生理后遗症会产生导致该患者群体发生ED的独特器质性和心理因素。使用β受体阻滞剂、地高辛和噻嗪类利尿剂的标准HF治疗可能因药物副作用而使性功能障碍恶化。这反过来可能导致患者为维持满意的性活动而进行错误尝试，从而不遵医嘱，进而导致心功能继发性恶化。本综述描述了HF患者中ED的独特方面。
