异噻菌胺抑制大鼠肝脏线粒体中ATP的合成。
Irgarol inhibits the synthesis of ATP in mitochondria from rat liver.
作者信息
Bragadin Marcantonio, Cima Francesca, Ballarin Loriano, Manente Sabrina
机构信息
Dipartimento di Scienze Ambientali, Università di Venezia, DD 2137, 30123 Venice, Italy.
出版信息
Chemosphere. 2006 Dec;65(10):1898-903. doi: 10.1016/j.chemosphere.2006.08.001. Epub 2006 Sep 18.
Abstract
The interactions of Irgarol with rat liver mithocondrial have been investigated. The results indicate that Irgarol inhibits the ATP synthesis. The analysis of the various steps involved in the ATP synthesis suggests that the inhibition is due to the opening of small-size pores.
摘要
已对杀藻胺与大鼠肝脏线粒体的相互作用进行了研究。结果表明，杀藻胺抑制ATP合成。对ATP合成所涉及的各个步骤的分析表明，这种抑制作用是由于小尺寸孔道的开放所致。
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