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植物CACTA元件的研究进展

Progress in plant CACTA elements.

作者信息

Tian Ping-Fang

机构信息

College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China.

出版信息

Yi Chuan Xue Bao. 2006 Sep;33(9):765-74. doi: 10.1016/S0379-4172(06)60109-1.

Abstract

Transposable elements are DNA fragments that can insert new chromosomal locations. On the basis of the mechanism of transposition, transposable elements were divided into two classes. Class 1 elements were retroelements that used reverse transposase to transpose by an RNA intermediate. Class 2 elements or DNA transposons transposed directly from DNA to DNA. Of the Class 2 elements, CACTA superfamily, so far identified exclusively in plants and previously regarded as low-copy-transposon for the conserved mechanism of propagation, recently received considerable interest because of their increasing evidence reiterating their high copies in some plant genomes. This article aimed at outlining CACTA elements with regard to their structure, transposition, and utilization.

摘要

转座元件是能够插入新的染色体位置的DNA片段。根据转座机制,转座元件被分为两类。第1类元件是逆转座子,它们利用逆转录转座酶通过RNA中间体进行转座。第2类元件或DNA转座子则直接从DNA转座到DNA。在第2类元件中,CACTA超家族目前仅在植物中被鉴定出来,由于其保守的传播机制,之前被认为是低拷贝转座子,但最近因其越来越多的证据表明在某些植物基因组中存在高拷贝数而受到广泛关注。本文旨在概述CACTA元件的结构、转座和应用。

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