Sankaranarayanan M, Chua L P, Ghista D N, Tan Y S
School of Mechanical & Production Engineering, Nanyang Technological University, 639798, Singapore.
J Med Eng Technol. 2006 Sep-Oct;30(5):269-82. doi: 10.1080/03091900500217281.
This paper presents the fluid dynamics of blood flow in a coronary bypass model of the aorto-right coronary bypass system. Three-dimensional computational fluid dynamic simulations are developed of the blood flow in coronary artery-bypass systems, using the computational fluid dynamics software (FLUENT 6.0.1). These blood flow simulations are performed within small intervals of the cardiac cycle, using input data consisting of physiological measurements of flow rates in the aorta, obtained from earlier studies. We have calculated the flow-field distributions of the velocity and the wall shear stress at four typical instants of the cardiac cycle, two during systole and two during the diastole phase. Plots of velocity vector and the wall shear stress are displayed in the aorto-graft-coronary arterial flow-field domain, providing an insight into the link between fluid dynamics and arterial diseases. The prime regions of disturbed flow patterns are at the entrance into the graft from the aorta and at the exit from the graft into the right coronary artery. Our objective is to obtain an understanding of how the coronary artery is perfused by the graft, and thereby into the factors affecting graft patency.
本文介绍了主动脉-右冠状动脉旁路系统冠状动脉搭桥模型中的血流流体动力学。利用计算流体动力学软件(FLUENT 6.0.1),对冠状动脉旁路系统中的血流进行了三维计算流体动力学模拟。这些血流模拟是在心动周期的小时间间隔内进行的,使用的输入数据包括从早期研究中获得的主动脉血流速率的生理测量值。我们计算了心动周期四个典型时刻的速度和壁面剪应力的流场分布,其中两个时刻在收缩期,两个时刻在舒张期。速度矢量图和壁面剪应力图显示在主动脉-移植物-冠状动脉流场区域,有助于深入了解流体动力学与动脉疾病之间的联系。血流模式紊乱的主要区域位于从主动脉进入移植物的入口处以及从移植物进入右冠状动脉的出口处。我们的目标是了解移植物如何灌注冠状动脉,从而了解影响移植物通畅的因素。