鼠李糖乳杆菌GG菌株调节大鼠对黄曲霉毒素B1的肠道吸收、粪便排泄及毒性。
Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B(1) in rats.
作者信息
Gratz S, Täubel M, Juvonen R O, Viluksela M, Turner P C, Mykkänen H, El-Nezami H
机构信息
Department of Clinical Nutrition, University of Kuopio, P.O. Box 1627, 70211 Kuopio, Finland.
出版信息
Appl Environ Microbiol. 2006 Nov;72(11):7398-400. doi: 10.1128/AEM.01348-06. Epub 2006 Sep 15.
Abstract
In this study, the modulation of aflatoxin B(1) (AFB(1)) uptake in rats by administration of the probiotic Lactobacillus rhamnosus GG was demonstrated. Fecal AFB(1) excretion in GG-treated rats was increased via bacterial AFB(1) binding. Furthermore, AFB(1)-associated growth faltering and liver injury were alleviated with GG treatment.
摘要
在本研究中，证实了通过给予益生菌鼠李糖乳杆菌GG可调节大鼠对黄曲霉毒素B1（AFB1）的摄取。经GG处理的大鼠粪便中AFB1排泄量因细菌与AFB1结合而增加。此外，GG处理减轻了与AFB1相关的生长发育迟缓及肝损伤。
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