Abzianidze E N
Georgian Med News. 2006 Aug(137):88-91.
The experiment was held on two groups of 40 grown-up white male rats. After the tests had bean finished by means of high-performance liquid chromatography method the quantity of monoamines (norepinephrine, serotonin and dopamine) was defined in hypothalamus, and the concentration of sex hormones (Follicle stimulating--FSH, Luteinizing hormone--LH, testosterone--T, estradiol--E(2)) was also defined by immunoferment method in the blood. The research showed that in both groups serotonin's level increased compared with the control group. In the first group its concentration increased to 147% and in the second one to 120%. As the rate of norepinephrine in the first group was increased by 41% against the background of anabolic steroid- -retabolil injections its concentration reduced to 90%. Its especially worth mentioning that as in the first case the concentration of dopamine was too reduced to 14% in the second case it made 70%. As a result of the research it was established that the concentration as T and E(2) as their regulator gonadotrophin hormones were decreased in the first group, but in condition of vibration pathology's correction with retabolil the rate of FSH and LH were within the norm, it follows that the rate of sexual steroids T and E(2) were within the norm.
该实验在两组各40只成年雄性白色大鼠上进行。通过高效液相色谱法完成测试后，测定下丘脑中单胺类物质（去甲肾上腺素、血清素和多巴胺）的含量，并采用免疫酶法测定血液中性激素（促卵泡激素——FSH、黄体生成素——LH、睾酮——T、雌二醇——E₂）的浓度。研究表明，与对照组相比，两组大鼠血清素水平均升高。第一组中其浓度升至147%，第二组升至120%。在注射合成代谢类固醇——康力龙的背景下，第一组去甲肾上腺素含量增加了41%，但其浓度降至90%。特别值得一提的是，在第一种情况下多巴胺浓度也降至14%，在第二种情况下则为70%。研究结果表明，第一组中作为其调节因子的促性腺激素T和E₂的浓度降低，但在用康力龙纠正振动病理学的情况下，FSH和LH的含量在正常范围内，由此可知性类固醇T和E₂的含量也在正常范围内。
