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[垂体 - 甲状腺内分泌轴激素对振动病理及其用液氧和合成代谢类固醇进行矫正的状况的反应]

[The reaction of hormones of hypophysis-thyroid gland's endocrinal axis on vibration pathology and on condition of it's correction with liquid oxygen and anabolic steroids].

作者信息

Abzianidze E N

出版信息

Georgian Med News. 2007 Jun(147):75-7.

PMID:17660607
Abstract

The experiment was held on white male rats. After the tests had been finished, by means of immunofermental method the concentration of thyroid (T3 and T4) and thyrotrophic (TSH) hormones were defined in the blood of animals in condition of vibropathology and it's correction with liquid oxygen and retabolil. The research showed, that the level of TSH, T3 and T4 decreased in condition of vibropathology and it's correction with anabolic steroid compare with control groups. But against of background liquid oxygen's injection the level of TSH increased, but the concentration of T3 and T4 were reduced compare with control group, though they were increased compare with the rest groups of experimental animals. As a result of the search, it was established, that the impact of vibration on the organism of male rats causes important changes in the hypophysis-thyroid gland's endocrinal axis, particularly it takes place the hypofunction of thyroid gland. And it's worth to mention that the correction of vibropathology with liquid oxygen cause positive influence and changes in the organism. There is a positively expressed normalization of thyroid and thyrotrophic hormones' concentration, but the correction of vibropathology with anabolic steroid has not been a successful one.

摘要

该实验以白色雄性大鼠为对象。测试完成后,采用免疫酶法测定了处于振动病状态以及用液氧和雷他必利进行矫正的动物血液中甲状腺激素(T3和T4)和促甲状腺激素(TSH)的浓度。研究表明,与对照组相比,处于振动病状态以及用合成代谢类固醇进行矫正时,TSH、T3和T4的水平降低。但是,与对照组相比,在注射液氧的情况下,TSH水平升高,T3和T4的浓度降低,不过与其他实验组动物相比它们有所升高。研究发现,振动对雄性大鼠机体的影响会导致垂体 - 甲状腺内分泌轴发生重要变化,特别是会出现甲状腺功能减退。值得一提的是,用液氧矫正振动病会对机体产生积极影响和变化。甲状腺和促甲状腺激素浓度有明显的正向正常化,但用合成代谢类固醇矫正振动病并不成功。

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