癌症幸存者的透明隔腔与侵入性回忆

Cavum septi pellucidi and intrusive recollections in cancer survivors.

作者信息

Matsuoka Yutaka, Nagamine Mitsue, Inagaki Masatoshi, Yoshikawa Eisho, Nakano Tomohito, Akechi Tatsuo, Kobayakawa Makoto, Hara Eriko, Imoto Shigeru, Murakami Koji, Uchitomi Yosuke

机构信息

Adult Mental Health Division, National Institute of Mental Health, National Center of Neurology and Psychiatry, Ogawahigashi 4-1-1, Kodaira, Tokyo 187-8553, Japan.

出版信息

Neurosci Res. 2006 Nov;56(3):344-6. doi: 10.1016/j.neures.2006.07.011. Epub 2006 Sep 18.

DOI:10.1016/j.neures.2006.07.011

PMID:16982105

Abstract

A previous study reported abnormally large cavum septi pellucidi (CSP) in posttraumatic stress disorder (PTSD). We utilized magnetic resonance imaging to examine the frequency of large CSP, as defined by Nopoulos et al. (1997), in cancer survivors with and without intrusive recollections in a sample identical to that of our previous study. The frequency of large CSP did not differ between the two groups. The results suggest that alteration in midline structures during the course of neurodevelopment may lead to severe PTSD, while subthreshold PTSD, such as intrusive recollections, appear not to be associated with such alterations.

摘要

先前的一项研究报告称，创伤后应激障碍（PTSD）患者的透明隔腔（CSP）异常增大。我们利用磁共振成像，在与我们先前研究相同的样本中，检查了有和没有侵入性回忆的癌症幸存者中，由诺普洛斯等人（1997年）定义的大CSP的出现频率。两组之间大CSP的出现频率没有差异。结果表明，神经发育过程中线结构的改变可能导致严重的PTSD，而阈下PTSD，如侵入性回忆，似乎与这种改变无关。