Dajkovic Alex, Lutkenhaus Joe
Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
J Mol Microbiol Biotechnol. 2006;11(3-5):140-51. doi: 10.1159/000094050.
It has become apparent that bacteria possess ancestors of the major eukaryotic cytoskeletal proteins. FtsZ, the ancestral homologue of tubulin, assembles into a cytoskeletal structure associated with cell division, designated the Z ring. Formation of the Z ring represents a major point of both spatial and temporal regulation of cell division. Here we discuss findings concerning the structure and the formation of the ring as well as its spatial and temporal regulation.
显而易见，细菌拥有主要真核细胞骨架蛋白的祖先。FtsZ是微管蛋白的同源祖先，它组装成与细胞分裂相关的细胞骨架结构，称为Z环。Z环的形成代表了细胞分裂在空间和时间上调控的一个主要关键点。在此，我们讨论关于该环的结构、形成以及其空间和时间调控的研究发现。
