How Protein Filaments Treadmill.
作者信息
Andreu José M
机构信息
Centro de Investigaciones Biológicas Margarita Salas, CSIC, Madrid, Spain.
出版信息
Biophys J. 2020 Aug 18;119(4):717-720. doi: 10.1016/j.bpj.2020.06.035. Epub 2020 Jul 17.
Abstract
摘要
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Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides.三种不同结合核苷酸的肌动蛋白丝冷冻电镜结构揭示的肌动蛋白聚合机制。
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FtsZ filaments have the opposite kinetic polarity of microtubules.FtsZ 丝呈现与微管相反的动力学极性。
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Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6191-E6200. doi: 10.1073/pnas.1802637115. Epub 2018 Jun 18.
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Structural transitions of F-actin upon ATP hydrolysis at near-atomic resolution revealed by cryo-EM.冷冻电镜揭示了接近原子分辨率的 F-肌动蛋白在 ATP 水解时的结构转变。
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