依那普利对NISAG大鼠肾脏肾小球结构特征的延迟效应。
Delayed effects of enalapril on structural characteristics of the glomerular apparatus in the kidneys of NISAG rats.
作者信息
Filyushina E E, Shmerling M D, Lazarev V A, Buzueva I I, Kudryashova D R, Markel A L, Yakobson G S
机构信息
Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.
出版信息
Bull Exp Biol Med. 2006 Feb;141(2):167-9. doi: 10.1007/s10517-006-0118-z.
Structural characteristics of renal glomeruli were studied in adult hypertensive NISAG rats (hereditary stress-induced hypertension) receiving antihypertensive drug enalapril, an inhibitor of angiotensin-converting enzyme, on days 28-58 of life. Treatment with enalapril (25 mg/kg perorally) in the early period of postnatal ontogeny produced delayed hypotensive and nephroprotective effects.
在成年NISAG大鼠（遗传性应激诱导型高血压）生命的第28至58天，研究了接受降压药物依那普利（一种血管紧张素转换酶抑制剂）治疗的肾小球结构特征。在出生后个体发育早期用依那普利（25毫克/千克口服）治疗产生了延迟的降压和肾保护作用。
Zotero 插件