产后早期个体发育期间的慢性应激对NISAG大鼠心肌和肾小球结构特征的影响

Effect of chronic stress during early postnatal ontogeny on structural characteristics of the myocardium and glomerular apparatus of the kidneys in NISAG rats.

作者信息

Shmerling M D, Filyushina E E, Korostyshevskaya I M, Lazarev V A, Maksimov V F, Buzueva I I, Kudryashova D R, Markel' A L, Yakobson G S

机构信息

Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk. M.D.Shmerling@.iph.ma.nsc.ru

出版信息

Bull Exp Biol Med. 2003 Jul;136(1):22-5. doi: 10.1023/a:1026072309673.

DOI:10.1023/a:1026072309673

PMID:14534602

Abstract

We studied structural characteristics of the myocardium and glomerular apparatus of the kidneys in 3-week- and 6-month-old male NISAG rats (hereditary stress-induced arterial hypertension) subjected to handling on days 1-21 of postnatal ontogeny. The animals were daily isolated from mothers for 10 min. Handling did not modulate the development of arterial hypertension and typical morphological signs in the myocardium and kidneys.

摘要

我们研究了3周龄和6月龄雄性NISAG大鼠（遗传性应激诱导性动脉高血压）在出生后个体发育第1 - 21天接受处理时心肌和肾脏肾小球装置的结构特征。这些动物每天与母亲隔离10分钟。处理并未调节动脉高血压的发展以及心肌和肾脏中的典型形态学特征。