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一名结节性硬化症患者患有两种不同的肾细胞癌和多发血管平滑肌脂肪瘤。

Two different renal cell carcinomas and multiple angiomyolipomas in a patient with tuberous sclerosis.

作者信息

Kang Sung Gu, Ko Young Hwii, Kang Seok Ho, Kim Jin, Kim Chul Hwan, Park Hong Seok, Moon Du Geon, Lee Jeong Gu, Kim Je Jong, Cheon Jun

机构信息

Department of Urology, Korea University School of Medicine, Seoul, Korea.

出版信息

Korean J Urol. 2010 Oct;51(10):729-32. doi: 10.4111/kju.2010.51.10.729. Epub 2010 Oct 21.

DOI:10.4111/kju.2010.51.10.729
PMID:21031096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2963789/
Abstract

We report a case of tuberous sclerosis associated with two histologically different renal cell carcinomas (RCCs) and multiple angiomyolipomas (AMLs) in the same kidney. A 43-year-old female was admitted to our hospital with left flank pain and a huge palpable mass in the left flank area. Abdominal computed tomography revealed two concurrent RCCs and multiple AMLs in the left kidney. Because of the clinical suspicion of RCC, the patient underwent left radical nephrectomy. On gross examination, the total size of the resected left kidney was 30.5×17×8 cm. Microscopically, the upper pole tumor features were consistent with chromophobe RCC and the midpole tumor was a clear-cell RCC. The multifocal masses in the remaining remnant parenchyma were AMLs. Six months after surgery, the patient is healthy without signs of tumor recurrence.

摘要

我们报告一例结节性硬化症患者，其同一侧肾脏中存在两种组织学类型不同的肾细胞癌（RCC）和多发血管平滑肌脂肪瘤（AML）。一名43岁女性因左侧腰痛及左侧腰区可触及巨大肿块入住我院。腹部计算机断层扫描显示左肾同时存在两个RCC和多个AML。由于临床怀疑为RCC，患者接受了左肾根治性切除术。大体检查显示，切除的左肾总大小为30.5×17×8 cm。显微镜下，上极肿瘤特征符合嫌色性RCC，中极肿瘤为透明细胞RCC。剩余肾实质中的多灶性肿块为AML。术后6个月，患者健康，无肿瘤复发迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/b70fbdafa4fc/kju-51-729-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/f6cd7b06a98e/kju-51-729-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/43263758dcaa/kju-51-729-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/843888f1729e/kju-51-729-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/dc3076f06d21/kju-51-729-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/b70fbdafa4fc/kju-51-729-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/f6cd7b06a98e/kju-51-729-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/43263758dcaa/kju-51-729-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/843888f1729e/kju-51-729-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/dc3076f06d21/kju-51-729-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/626d/2963789/b70fbdafa4fc/kju-51-729-g005.jpg

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