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改良布莱洛克 - 陶西格分流术新技术的患者选择标准及结果

Criterions for selection of patients for, and results of, a new technique for construction of the modified Blalock-Taussig shunt.

作者信息

Chowdhury Ujjwal K, Venugopal Panangipalli, Kothari Shyam S, Saxena Anita, Talwar Sachin, Subramaniam Ganapathy, Singh Rajvir, Pradeep Kizakke K, Sathia Siddhartha, Kumar A Sampath

机构信息

Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Cardiol Young. 2006 Oct;16(5):463-73. doi: 10.1017/S1047951106000631.

Abstract

BACKGROUND

We describe alternative surgical techniques for construction of systemic-to-pulmonary arterial shunts, and propose criterions for their application in selected patients.

PATIENTS AND METHODS

We constructed a variety of modified systemic-to-pulmonary arterial shunts, using polytetrafluoroethylene grafts, in 92 selected patients with cyanotic congenital heart disease and anomalies of the aortic arch and systemic veins. Their age ranged from 7 days to 3.6 years, with a mean of 7.08 months. We performed 88 operations through a thoracotomy. Of this cohort, 60 patients underwent a second-stage operation, with 15 receiving a superior cavopulmonary connection, 16 a total cavopulmonary connection, and 29 proceeding to biventricular repair after a mean interval of 15.6 months. We have 21 patients awaiting their second or final stage of palliation.

RESULTS

There were five early (5.4%) and six late deaths (6.8%), two of which were related to construction of the shunts. At a mean follow-up of 45.29 months, the increase in diameter of pulmonary trunk and its right and left branches was uniform and significant (p value less than 0.001). Pulmonary arterial distortion requiring correction at the time of second-stage operation was observed in 5 patients (6.1%). Adequate overall palliation was achieved in 98% of the cohort at 8 months, 91% at 12 months, and 58% at 18 months.

CONCLUSIONS

Patients with a right- or left-sided aortic arch and right-sided descending thoracic aorta, those with anomalies of systemic venous drainage masking the origin of great arterial branches, and those with disproportionately small subclavian arteries, constitute the ideal candidates for our suggested modification of the construction of a modified Blalock-Taussig shunt. The palliation provided by these shunts was satisfactory, with predictable growth of pulmonary arteries, insignificant distortion in the great majority, and easy take-down.

摘要

背景

我们描述了用于构建体肺分流的替代手术技术,并提出了其在特定患者中应用的标准。

患者与方法

我们使用聚四氟乙烯移植物,为92例患有青紫型先天性心脏病以及主动脉弓和体静脉异常的特定患者构建了多种改良的体肺分流。他们的年龄从7天至3.6岁不等,平均为7.08个月。我们通过开胸手术进行了88例手术。在该队列中,60例患者接受了二期手术,其中15例接受了上腔静脉-肺动脉连接,16例接受了全腔静脉-肺动脉连接,29例在平均间隔15.6个月后进行了双心室修复。我们有21例患者正在等待二期或最终姑息治疗阶段。

结果

有5例早期死亡(5.4%)和6例晚期死亡(6.8%),其中2例与分流构建有关。平均随访45.29个月时,肺动脉干及其左右分支的直径增加均匀且显著(p值小于0.001)。5例患者(6.1%)在二期手术时观察到需要矫正的肺动脉扭曲。该队列中98%的患者在8个月时实现了充分的总体姑息治疗,12个月时为91%,18个月时为58%。

结论

右侧或左侧主动脉弓以及右侧胸降主动脉的患者、体静脉引流异常掩盖大动脉分支起源的患者以及锁骨下动脉不成比例细小的患者,是我们建议的改良布莱洛克-陶西格分流构建的理想候选者。这些分流提供的姑息治疗效果令人满意,肺动脉可预测地生长,绝大多数无明显扭曲,且易于拆除。

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