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罕见细菌感染导致的椎体成形术通过手术解决:一种常见手术罕见且危及生命的并发症:病例报告及文献综述

Infected vertebroplasty due to uncommon bacteria solved surgically: a rare and threatening life complication of a common procedure: report of a case and a review of the literature.

作者信息

Alfonso Olmos Matias, Silva González Alvaro, Duart Clemente Julio, Villas Tomé Carlos

机构信息

Department of Orthopaedic Surgery, University Clinic of Navarra, Navarra, Spain.

出版信息

Spine (Phila Pa 1976). 2006 Sep 15;31(20):E770-3. doi: 10.1097/01.brs.0000240202.91336.99.

DOI:10.1097/01.brs.0000240202.91336.99
PMID:16985448
Abstract

STUDY DESIGN

Case report.

OBJECTIVE

The aim of this work is to describe a case of infected vertebroplasty due to uncommon bacteria solved surgically with 2 years of follow-up and to discuss 6 other cases found in literature.

SUMMARY OF BACKGROUND DATA

Vertebroplasty is a well-known and useful technique for the treatment of painful osteoporotic vertebral fractures. Complications, such as cord or root compression or pulmonary embolisms, are infrequent and are mainly related with the frequent escape of cement throughout the vertebral veins. Infection is even more rare, but when it occurs is difficult to manage and can be a life-threatening complication.

METHODS

A 63-year-old-man had a spondylitis of L2 after vertebroplasty. The patient was initially managed with antibiotics without clinical improvement. Surgical treatment by anterior debridement and anterior and posterior stabilization was done. The bacteria isolated from the intraoperative cultures were Serratia marcescens, Stenotrophomonas maltophilia, and Burkholderia cepacia. After surgery, the patient was treated with antibiotics for 3 month.

RESULTS

After 2 years of follow-up, the patient was free of pain, without signs of infection, and a correct fusion was achieved.

CONCLUSION

When facing an infected vertebroplasty, initial conservative treatment with needle biopsy culture and antibiotic administration are a rational option to start. If this treatment fails, surgical debridement is then indicated in order to remove the infected tissue and the acrylic cement and to stabilize the spine. Although this can be an effective treatment, it could be a difficult and hazardous surgical procedure.

摘要

研究设计

病例报告。

目的

本文旨在描述一例因罕见细菌感染导致的椎体成形术病例,该病例通过手术治疗并进行了2年随访,同时讨论文献中发现的其他6例病例。

背景资料总结

椎体成形术是治疗骨质疏松性椎体骨折疼痛的一种知名且有效的技术。诸如脊髓或神经根受压或肺栓塞等并发症并不常见,主要与骨水泥频繁经椎静脉渗漏有关。感染更为罕见,但一旦发生则难以处理,且可能是危及生命的并发症。

方法

一名63岁男性在椎体成形术后发生L2椎体骨髓炎。患者最初接受抗生素治疗,但临床症状无改善。遂行前路清创及前后路固定手术治疗。术中培养分离出的细菌为粘质沙雷菌、嗜麦芽窄食单胞菌和洋葱伯克霍尔德菌。术后患者接受了3个月的抗生素治疗。

结果

经过2年随访,患者无痛,无感染迹象,实现了正确的融合。

结论

面对感染性椎体成形术时,首先进行针吸活检培养及给予抗生素的保守治疗是合理的起始选择。若该治疗失败,则需进行手术清创,以清除感染组织和丙烯酸骨水泥并稳定脊柱。尽管这可能是一种有效的治疗方法,但可能是一项困难且危险的外科手术。

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