Watkins Robert G, Hussain Nazakat, Freeman Brian J, Grevitt Michael P, Webb John K
Los Angeles Spine Surgery Institute, Los Angeles, CA 90057, USA.
Spine (Phila Pa 1976). 2006 Sep 15;31(20):2337-42. doi: 10.1097/01.brs.0000240201.14208.68.
This is a retrospective, sequential cohort study of 34 patients treated by anterior instrumented fusion with single solid rod, single screw constructs with at least 2-year follow-up. Sixteen of the patients received structural grafts as interbody spacers in disc levels below T12, while the other 18 patients received only morselized rib autograft.
To determine if structural interbody grafts preserve sagittal alignment better than morselized rib autograft.
Some studies have shown that structural grafts are more effective in preserving sagittal alignment, while others have found them to be no more effective than morselized rib graft.
Anterior-posterior radiographs were measured for primary, secondary, and fractional Cobb curves, and C7-sacrum plumb lines. Lateral radiographs were measured for: T5-HIV (highest instrumented vertebrae), instrumented levels, LIV (lowest instrumented vertebrae)-S1, T12-LIV, and T12-S1 angles, C7-sacrum plumb lines, and LID-A (lowest instrumented disc-angle).
The increase in kyphosis from preoperative to follow-up radiographs of the angle between T12-LIV was significantly more for the patients with morselized rib graft compared with those with structural grafts, 9 degrees and 1 degree, respectively (P < 0.05).
The structural grafts placed in disc spaces below T12 were able to maintain sagittal alignment over this region, while the spines that received only morselized rib graft collapsed into kyphosis.
这是一项回顾性、连续性队列研究,纳入了34例接受前路单根实心棒、单枚螺钉固定融合治疗且随访至少2年的患者。16例患者在T12以下椎间盘节段接受结构性植骨作为椎间融合器,而另外18例患者仅接受碎块状肋骨自体骨移植。
确定结构性椎间植骨在维持矢状位对线方面是否比碎块状肋骨自体骨移植更有效。
一些研究表明,结构性植骨在维持矢状位对线方面更有效,而另一些研究则发现它们并不比碎块状肋骨植骨更有效。
测量前后位X线片上的原发、继发和分节段Cobb角以及C7-骶骨垂线。测量侧位X线片上的:T5-最高固定椎体(HIV)、固定节段、最低固定椎体(LIV)-S1、T12-LIV和T12-S1角、C7-骶骨垂线以及最低固定椎间盘角(LID-A)。
与接受结构性植骨的患者相比,接受碎块状肋骨植骨的患者从术前到随访X线片上T12-LIV角的后凸增加更为明显,分别为9度和1度(P<0.05)。
置于T12以下椎间盘间隙的结构性植骨能够在该区域维持矢状位对线,而仅接受碎块状肋骨植骨的脊柱则出现后凸畸形。