Korb L J, Brawer M K
Rev Urol. 2001 Winter;3(1):51-62.
Modern ultrasound-guided prostate brachytherapy is rapidly changing the way localized prostate cancer is managed. With routine use of prostate-specific antigen screening, prostate cancer is being diagnosed in younger men, who are understandably concerned about the morbidity of radical treatments that may significantly decrease their quality of life. Numerous studies of prostate brachytherapy have shown the excellent disease control rates achieved while maintaining low levels of urinary and erectile difficulties. This report examines a modern implant method of brachytherapy; describes patient selection for brachytherapy, alone and in combination with external beam therapy; and presents results from a series of men followed for 12 years.
现代超声引导下的前列腺近距离放射治疗正在迅速改变局限性前列腺癌的治疗方式。随着前列腺特异性抗原筛查的常规使用，前列腺癌在较年轻男性中被诊断出来，他们理所当然地担心根治性治疗可能会显著降低其生活质量而带来的发病率。大量关于前列腺近距离放射治疗的研究表明，在保持低水平的排尿和勃起功能障碍的同时，可实现出色的疾病控制率。本报告研究了一种现代的近距离放射治疗植入方法；描述了单独及与外照射治疗联合使用时近距离放射治疗的患者选择；并呈现了对一组男性随访12年的结果。
