Kuzik Iu I
Arkh Patol. 2006 Jul-Aug;68(4):57-61.
The paper reviews the data available in the literature on the etiology, pathogenesis, pathomorphology and examinations of patients with fibromuscular dysplasia. The types of fibromuscular dysplasia are discussed in detail in relation to the damage to vascular wall layers. These include intimal fibroplasia, medial hyperplasia, medial fibroplasias, and perimedial fibroplasia with a well-defined definition pathomorphological and angiographic criteria. The role of various etiological factors in the development of fibromuscular dysplasia is given, by presenting the genetical, mechanical, ishemic, humoral, and hormonal hypothesis of pathogenesis; differential diagnostic features are determined. Emphasis is laid on the necessity and topicality of studying the etiology, pathogenesis, and pathomorphology of dysplasia to gain a better insight into this disease, to choose an effective treatment.