Stokes J B, Bonsib S M, McBride J W
Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, USA.
Arch Intern Med. 1996;156(22):2611-4.
A woman presented with a rapid onset of hypertension, angina pectoris, peripheral vascular disease, renal involvement, and a large liver cyst. Surgical removal of the liver cyst precipitated renal and liver failure and a terminal arrhythmia. At autopsy, there was intimal fibromuscular dysplasia involving the arteries to the heart, liver, kidneys, and intestines and evidence of recent infarction of the intestines, kidney, and liver. This case illustrates that intimal fibromuscular dysplasia (FMD) can be a diffuse and rapidly progressive disease. Some treatments currently being evaluated for preventing restenosis following angioplasty may find use in treating this uncommon disease.
一名女性患者出现高血压、心绞痛、外周血管疾病、肾脏受累以及一个大的肝囊肿，病情迅速进展。手术切除肝囊肿后引发了肾衰竭、肝衰竭及致命性心律失常。尸检发现，心脏、肝脏、肾脏和肠道的动脉存在内膜纤维肌发育不良，且有肠道、肾脏和肝脏近期梗死的证据。该病例表明，内膜纤维肌发育不良（FMD）可能是一种弥漫性且进展迅速的疾病。目前正在评估的一些预防血管成形术后再狭窄的治疗方法，可能会用于治疗这种罕见疾病。
