Hawkins K, Behrens M M
Br J Ophthalmol. 1975 Jun;59(6):334-7. doi: 10.1136/bjo.59.6.334.
A patient with multiple sclerosis and bilateral retrochiasmal visual field defects is reported. Homonymous field defects are rare in multiple sclerosis despite the frequency of pathological involvement of the retrochiasmal visual pathways. A higher incidence might be found with a higher index of suspicion and careful visual field testing with qualitative confrontation technique. Other reasons for the infrequent clinical detection of retrochiasmal lesions are considered. Such lesions may exist without demonstrable defect. This may be explained by anatomical factors, for example, fibre arrangement, or physiological factors, such as, geniculate or retrogeniculate integration. Lesions producing demonstrable defects may be asymptomatic because they: affect only the peripheral field, are small scotomas that do not impair visual acuity, affect only one eye, or occur late in the course of disease when masked by optic nerve involvement.
本文报道了一例患有多发性硬化症且伴有双侧视交叉后视野缺损的患者。尽管视交叉后视觉通路的病理受累较为常见,但同向性视野缺损在多发性硬化症中却很少见。若提高怀疑指数并采用定性对照技术进行仔细的视野检查,可能会发现更高的发病率。文中还考虑了视交叉后病变临床检出率低的其他原因。此类病变可能存在但无明显缺损。这可能是由解剖学因素(如纤维排列)或生理学因素(如膝状体或膝状体后整合)所致。产生明显缺损的病变可能无症状,因为它们:仅影响周边视野、是不损害视力的小暗点、仅影响一只眼睛,或在疾病后期因视神经受累而被掩盖。