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加拿大原住民重症疾病的分布及决定因素。一项基于人群的评估。

Distribution and determinants of critical illness among status Aboriginal Canadians. A population-based assessment.

作者信息

Laupland Kevin B, Karmali Shahzeer, Kirkpatrick Andrew W, Crowshoe Lindsay, Hameed S Morad

机构信息

Department of Critical Care Medicine, Calgary Health Region, University of Calgary, Calgary, Alberta, Canada T2L 2K8.

出版信息

J Crit Care. 2006 Sep;21(3):243-7. doi: 10.1016/j.jcrc.2006.03.012.

Abstract

PURPOSE

The aim of the study is to determine the incidence, demographic risk factors, and outcomes of critical illness among all adult status Aboriginal Canadians (SACs) admitted to intensive care units (ICUs).

PATIENTS AND METHODS

A population-based cohort was conducted among adult residents of the Calgary Health Region admitted to ICUs between May 1999 and April 2002. Patients were classified as SAC based on an alternate premium arrangement field within their Alberta personal health number.

RESULTS

The annual incidence of critical illness among SACs of 620.6 per 100,000 was significantly higher than the non-SAC population of 302.6 per 100,000 (RR, 2.1; 95% CI, 1.78-2.35); this was due to a 3-fold higher admission rate to the multisystem ICUs among SAC (579.6 per 100,000/y) as compared with non-SAC patients (210.7 per 100,000/y; RR, 2.75; 95% confidence interval [CI], 2.37-3.17). The highest risk for ICU admission among SAC patients was observed in those aged 20 to 49 years, and the incidence was higher in males than females (772.3 vs 479.8 per 100,000/y; RR, 1.6; 95% CI, 1.21-2.14). Although the in-hospital case-fatality rate was only slightly higher among SAC (18%, 38/212) as compared with non-SAC patients (922/7,159; 13%; RR, 1.39; 95% CI, 1.04-1.87), the annual mortality rate was much higher (146.4 per 100,000 for SAC vs 60.9 per 100,000 for non-SAC; RR, 2.40; 95% CI, 1.78-3.19).

CONCLUSION

This study demonstrates that SACs have an increased burden of critical illness as compared with the general non-SAC population and supports further research aimed at exploring means to reduce its adverse impact in this population.

摘要

目的

本研究旨在确定入住重症监护病房(ICU)的所有成年原住民加拿大居民(SAC)中危重病的发病率、人口统计学风险因素及预后情况。

患者与方法

对1999年5月至2002年4月期间入住卡尔加里健康地区ICU的成年居民进行基于人群的队列研究。根据艾伯塔省个人健康号码中的替代保费安排字段将患者分类为SAC。

结果

SAC中危重病的年发病率为每10万人620.6例,显著高于非SAC人群的每10万人302.6例(相对风险[RR],2.1;95%置信区间[CI],1.78 - 2.35);这是由于SAC入住多系统ICU的比例(每10万人/年579.6例)比非SAC患者(每10万人/年210.7例;RR,2.75;95%置信区间[CI],2.37 - 3.17)高出3倍。SAC患者中,20至49岁人群入住ICU的风险最高,且男性发病率高于女性(每10万人/年772.3例对479.8例;RR,1.6;95% CI,1.21 - 2.14)。尽管SAC患者的院内病死率仅略高于非SAC患者(18%,38/212对922/7159;13%;RR,1.39;95% CI,1.04 - 1.87),但年死亡率要高得多(SAC为每10万人146.4例,非SAC为每10万人60.9例;RR,2.40;95% CI,1.78 - 3.19)。

结论

本研究表明,与一般非SAC人群相比,SAC的危重病负担有所增加,并支持进一步开展研究以探索减轻该人群不良影响的方法。

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