Moghadaszadeh Behzad, Beggs Alan H
Children's Hospital Boston, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Physiology (Bethesda). 2006 Oct;21:307-15. doi: 10.1152/physiol.00021.2006.
In the last few decades, the importance of selenium in human health has been the subject of numerous studies. It is believed that the physiological effects of selenium occur mainly through the function of selenoproteins, which incorporate selenium in the form of one or more selenocysteine residues. Recent advances in understanding the complex regulation of selenoprotein synthesis and functional characterization of several members of the selenoprotein family have contributed to an improved comprehension of the role(s) of selenium in human health and the great diversity of physiological pathways influenced by this trace element.
在过去几十年里，硒在人类健康中的重要性一直是众多研究的主题。人们认为，硒的生理作用主要通过硒蛋白的功能来实现，硒蛋白以一个或多个硒代半胱氨酸残基的形式结合硒。在理解硒蛋白合成的复杂调控以及硒蛋白家族几个成员的功能特性方面的最新进展，有助于更好地理解硒在人类健康中的作用以及受这种微量元素影响的生理途径的巨大多样性。
