Demidchik E P, Kruglova N E, Minaĭlo T I, Gauptman A E, Koren' T A, Gedrevich Z E, Sevkovskiĭ Ia I
Lab Delo. 1990(7):16-8.
The authors have used radioimmunoassay to measure blood serum thyroglobulin (TG) in 257 patients with benign processes and 118 ones with carcinoma of the thyroid and came to a conclusion that this method is unfit for the differential diagnosis between these conditions. Serum TG level is in good correlation with the results of treatment of thyroid carcinoma patients: in radically treated ones blood serum TG level reduces to the norm, and when recurrences or metastases develop it significantly increases. Therefore, radioimmunoassay is recommended for early detection of thyroid carcinoma recurrences and metastases in follow-up of patients with this condition.
作者使用放射免疫分析法对257例甲状腺良性疾病患者和118例甲状腺癌患者的血清甲状腺球蛋白(TG)进行了检测,得出该方法不适用于这两种疾病鉴别诊断的结论。血清TG水平与甲状腺癌患者的治疗结果密切相关:根治性治疗的患者血清TG水平降至正常,而当复发或转移发生时则显著升高。因此,推荐使用放射免疫分析法对甲状腺癌患者进行随访,以早期发现复发和转移。