Peters E J G, Kauffmann R H, Blok P
Department of Internal Medicine, Haga Hospital, location Leyenburg, the Hague, the Netherlands.
Neth J Med. 2006 Sep;64(8):302-6.
We describe four cases of HIV-positive patients, two from Surinam, one from the Dutch Antilles and one from Nigeria, who presented with a febrile illness and a high lactate dehydrogenase plasma level. In all four, the diagnosis of disseminated histoplasmosis was made, in three of them by liver biopsy. Two patients had retinal abnormalities compatible with a systemic fungal infection. Three patients were treated successfully with antifungal agents. One patient died. Between 2000 and 2006, only 14 patients with HIV have been found to have histoplasmosis in the Netherlands. Although histoplasmosis is not endemic in the Netherlands, physicians are more likely to see cases because of a growing number of HIV -positive immigrants from endemic regions.
我们描述了4例HIV阳性患者，其中2例来自苏里南，1例来自荷属安的列斯群岛，1例来自尼日利亚，他们均表现为发热性疾病且血浆乳酸脱氢酶水平升高。所有4例均被诊断为播散性组织胞浆菌病，其中3例经肝活检确诊。2例患者有与系统性真菌感染相符的视网膜异常。3例患者接受抗真菌药物治疗成功。1例患者死亡。2000年至2006年期间，在荷兰仅发现14例HIV患者患有组织胞浆菌病。尽管组织胞浆菌病在荷兰并非地方性疾病，但由于来自流行地区的HIV阳性移民数量不断增加，医生更有可能见到此类病例。
