Ebran Jean-Philippe, Jensen Christina M, Johannesen Sine A, Karaffa Jakob, Lindsay Karl B, Taaning Rolf, Skrydstrup Troels
Center for Insoluble Proteins Structures, Department of Chemistry, Interdisciplinary Nanoscience Center, University of Aarhus, 8000, Aarhus C, Denmark.
Org Biomol Chem. 2006 Oct 7;4(19):3553-64. doi: 10.1039/b608028f. Epub 2006 Sep 1.
In this perspective, an overview of our experiences on the application of samarium diiodide in organic synthesis for the preparation of amino acid and peptide analogues is presented. Three different carbon-carbon bond forming reactions are discussed, including side chain introductions, gamma-amino acid synthesis and acyl-like radical additions for the construction of C-C mimics of the peptidic bonds.
从这个角度出发，本文概述了我们在有机合成中应用二碘化钐制备氨基酸和肽类似物的经验。文中讨论了三种不同的碳-碳键形成反应，包括侧链引入、γ-氨基酸合成以及用于构建肽键碳-碳模拟物的类酰基自由基加成反应。
