Kudo H, Tanaka M, Urui S, Suzuki H, Tamaki N, Matsumoto S
Department of Neurosurgery, Kobe University School of Medicine.
Neurol Med Chir (Tokyo). 1990 May;30(5):334-8. doi: 10.2176/nmc.30.334.
A 74-year-old male was admitted because of severe headache, vertigo, and vomiting. A computed tomographic scan showed heterogeneously enhanced tumors in the supra- and the infratentorial regions, apparently attached to the cerebellar tentorium. He died 2 months after the onset despite external decompression and a ventriculo-peritoneal shunt. The autopsy showed both tumors were intra-axial and not attached to the dura mater including the cerebellar tentorium. The histological diagnosis of either tumor was glioblastoma multiforme. This case could be classified as multicentric gliomas. In the 23 reported cases, including our case, most died soon after the onset of symptoms. Some, however, with low grade tumors had a comparatively long life span after the onset. It is, therefore, important to investigate the histology of these tumors for correct prognosis.
一名74岁男性因严重头痛、眩晕和呕吐入院。计算机断层扫描显示幕上和幕下区域有不均匀强化的肿瘤，明显附着于小脑幕。尽管进行了外部减压和脑室-腹腔分流术，但他在发病后2个月死亡。尸检显示两个肿瘤均位于轴内，未附着于包括小脑幕在内的硬脑膜。两个肿瘤的组织学诊断均为多形性胶质母细胞瘤。该病例可归类为多中心胶质瘤。在包括我们病例在内的23例报告病例中，大多数在症状出现后不久死亡。然而，一些低级别肿瘤患者在发病后有相对较长的生存期。因此，为了正确判断预后，研究这些肿瘤的组织学很重要。
