Itoh J, Usui K, Itoh M, Hashizume Y
Department of Neurosurgery, Gifu Prefectural Tajimi Hospital.
Neurol Med Chir (Tokyo). 1990 May;30(5):339-45. doi: 10.2176/nmc.30.339.
A case of malignant ependymoma with extracranial metastases is reported. A 59-year-old male was admitted to our hospital with vomiting and ataxia. Following computed tomographic (CT) scanning indicating a ring-like enhanced mass in the cerebellum, the tumor was subtotally removed in December, 1985. Histological diagnosis was malignant ependymoma. A second operation was performed in February, 1987, due to recurrence of the tumor in the fourth ventricle. Postoperative radiation therapy at a total dose of 7780 rads was given over 2 years. Eleven months after radiation therapy was completed, he reported cough and multiple skin metastases. Chest x-rays showed metastases at the right hilus. Repeated CT scans revealed separate frontal cerebral metastatic tumors. He died of respiratory insufficiency. Extracranial metastases of infratentorial ependymoma to the skin and lung are rare pathological entities.
报告了1例伴有颅外转移的恶性室管膜瘤。一名59岁男性因呕吐和共济失调入院。计算机断层扫描（CT）显示小脑有环状强化肿块，1985年12月肿瘤次全切除。组织学诊断为恶性室管膜瘤。1987年2月因肿瘤在第四脑室复发再次手术。术后2年进行了总量为7780拉德的放射治疗。放疗结束11个月后，他出现咳嗽和多处皮肤转移。胸部X线显示右肺门转移。重复CT扫描发现额叶有独立的脑转移瘤。他死于呼吸功能不全。幕下室管膜瘤转移至皮肤和肺部是罕见的病理情况。
