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极性吻合血管对灌注猫肾的自身调节以及水和钠尿排泄的影响。

The influence of the polar anastomotic vessels on autoregulation and the urinary excretion of water and sodium by perfused cat kidneys.

作者信息

Lockett M F

出版信息

J Physiol. 1967 Dec;193(3):649-60. doi: 10.1113/jphysiol.1967.sp008385.

DOI:10.1113/jphysiol.1967.sp008385
PMID:16992303
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1365520/
Abstract
  1. Cat kidneys have been perfused from pump-oxygenator and from heart-lung circuits.2. Kidneys perfused from the pump-oxygenator circuit excreted more water and sodium and showed higher values for sodium: potassium in urine than kidneys perfused from heart-lung circuits. Renal plasma flow and the clearances of creatinine and p-aminohippuric acid were similar for preparations perfused by the two different methods.3. Dorsal and ventral polar anastomotic vessels appeared to communicate directly with sheaves of vasa recta in the kidneys of young cats through interlobar vessels.4. Ligature of these polar anastomotic vessels impaired autoregulation of blood flow in perfused cat kidneys.5. Open drainage from these polar vessels during perfusion increased the rates of excretion of water and sodium.6. Histological preparations made from kidneys perfused from pump-oxygenator and from heart-lung circuits for periods of 5-6(1/2) hr showed that the nephrons remain undamaged. The diameters of the tubules correlated with the rates of urine flow immediately before fixation.
摘要

  1. 已使用泵氧合器和心肺循环装置对猫肾进行灌注。

  2. 用泵氧合器循环灌注的肾脏排出的水分和钠更多，且尿中钠与钾的比值高于用心肺循环装置灌注的肾脏。两种不同灌注方法制备的肾脏，其肾血浆流量以及肌酐和对氨基马尿酸的清除率相似。

  3. 在幼猫肾脏中，背侧和腹侧极吻合血管似乎通过叶间血管与直小血管束直接相通。

  4. 结扎这些极吻合血管会损害灌注猫肾中血流的自动调节。

  5. 灌注期间从这些极血管进行开放引流可提高水和钠的排泄率。

  6. 用泵氧合器和心肺循环装置对肾脏进行5至6（1/2）小时灌注后制作的组织学标本显示，肾单位未受损伤。肾小管直径与固定前的尿流速率相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ed/1365520/c06d754fe759/jphysiol01114-0174-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ed/1365520/64c62d399f5b/jphysiol01114-0170-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ed/1365520/784b5f4f333f/jphysiol01114-0171-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ed/1365520/c06d754fe759/jphysiol01114-0174-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ed/1365520/64c62d399f5b/jphysiol01114-0170-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ed/1365520/784b5f4f333f/jphysiol01114-0171-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96ed/1365520/c06d754fe759/jphysiol01114-0174-a.jpg

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2
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J Physiol. 1967 Dec;193(3):671-8. doi: 10.1113/jphysiol.1967.sp008387.
3
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本文引用的文献

1
On some conditions affecting the perfusion of isolated mammalian organs.关于一些影响离体哺乳动物器官灌注的条件。
J Physiol. 1924 Dec 23;59(4-5):340-4. doi: 10.1113/jphysiol.1924.sp002189.
2
Hyperglycaemic and phlorhizin glycosuria in the heart-lung-kidney preparation.心肺肾制备中的高血糖和根皮苷性糖尿
J Physiol. 1924 May 23;58(6):433-40. doi: 10.1113/jphysiol.1924.sp002145.
3
The relative importance of the factors concerned in the formation of the urine.尿液形成过程中相关因素的相对重要性。
从活化肌肉的静脉血和收缩肌肉中分离出一种与D-醛固酮18-单乙酸酯非常相似的物质。
J Physiol. 1969 Oct;204(2):435-42. doi: 10.1113/jphysiol.1969.sp008922.
4
A renally active substance from heart muscle and from blood.一种来自心肌和血液的具有肾脏活性的物质。
J Physiol. 1968 May;196(1):101-9. doi: 10.1113/jphysiol.1968.sp008497.
5
Renal actions of dihydroergocristine and of phentolamine in anaesthetized cats.双氢麦角汀和酚妥拉明对麻醉猫的肾脏作用。
Br J Pharmacol. 1969 Nov;37(3):595-608. doi: 10.1111/j.1476-5381.1969.tb08498.x.
J Physiol. 1923 Aug 16;57(6):451-6. doi: 10.1113/jphysiol.1923.sp002083.
4
On secretion by the isolated kidney.关于离体肾脏的分泌。
J Physiol. 1922 Jul 21;56(5):353-8. doi: 10.1113/jphysiol.1922.sp002017.
5
A comparative study of renal interstitial pressure.肾间质压力的比较研究。
Am J Physiol. 1952 Apr;169(1):180-7. doi: 10.1152/ajplegacy.1952.169.1.180.
6
[Localization of the concentration process in the kidney by direct kryoscopy].[通过直接冰点测定法对肾脏中浓缩过程的定位]
Helv Physiol Pharmacol Acta. 1951 Jun;9(2):196-207.
7
[Hemodynamics of kidney medullary substance. Part I. Capillary passage time, blood volume, circulation, tissue hematocrit and oxygen consumption of kidney medullary substance in situ].[肾髓质物质的血流动力学。第一部分。原位肾髓质物质的毛细血管通过时间、血容量、循环、组织血细胞比容和氧消耗]
Pflugers Arch Gesamte Physiol Menschen Tiere. 1960;270:251-69.
8
Mechanisms of autoregulation in isolated perfused kidney.离体灌注肾的自身调节机制。
Proc Soc Exp Biol Med. 1960 Feb;103:373-5. doi: 10.3181/00379727-103-25524.
9
Tissue pressure as a causal factor in the autoregulation of blood flow in the isolated perfused kidney.组织压力作为离体灌注肾脏血流自动调节的一个因果因素。
Am J Physiol. 1959 Aug;197:309-12. doi: 10.1152/ajplegacy.1959.197.2.309.
10
THE MECHANISM AND PREVENTION OF PLATELET ADHESION AND AGGREGATION CONSIDERED IN RELATION TO ARTERIAL THROMBOSIS.从动脉血栓形成角度探讨血小板黏附与聚集的机制及预防
Blood. 1964 Sep;24:309-14.