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青蛙皮肤神经左右化学特异性测试。

Test for left-right chemospecificity in frog cutaneous nerves.

作者信息

Scott M Y, Sperry R W

出版信息

Brain Behav Evol. 1975;11(1):60-72. doi: 10.1159/000123625.

DOI:10.1159/000123625
PMID:169951
Abstract

Studies of the effects of competitive reinnervation by left and right cutaneous nerves were carried out in Rana pipiens in an effort to test for the existence of left-right biochemical differentiation of neural tissue. The dorsal cutaneous nerves were cut, transposed and allowed to regenerate under different conditions of denervation and competition and the resultant reinnervation and reflex patterns were determined by behavioral and electrophysiological mapping techniques. Contrary to earlier findings, there was no indication in the present investigation that the growth patterns were influenced by the laterality of the fibers. Other factors such as availability of terminal sites created by complete or partial denervation and the tendency of fibers to seek terminal connections seemed to override any qualifications imposed by the existence of lateral specificity on the formation of terminal contacts.

摘要

为了检验神经组织左右生化分化的存在,对牛蛙进行了左右皮神经竞争性再支配效应的研究。切断背皮神经,进行移位,并使其在不同的去神经和竞争条件下再生,通过行为和电生理绘图技术确定由此产生的再支配和反射模式。与早期的发现相反,本研究没有迹象表明生长模式受纤维的左右侧性影响。其他因素,如完全或部分去神经所产生的终末位点的可用性,以及纤维寻求终末连接的倾向,似乎压倒了侧特异性对终末接触形成所施加的任何限制。

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引用本文的文献

1
Neurophysiological and behavioral evidence for selective reinnervation in skin-grafted Rana pipiens.皮肤移植的豹蛙选择性再支配的神经生理学和行为学证据。
Proc Natl Acad Sci U S A. 1977 Dec;74(12):5749-53. doi: 10.1073/pnas.74.12.5749.