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减肥手术对心血管和肌肉骨骼疾病的影响。

Impact of bariatric surgery on cardiovascular and musculoskeletal morbidity.

作者信息

Sampalis John S, Sampalis Fotini, Christou Nicolas

机构信息

Department of Surgery, McGill University Health Centre, Montreal, Quebec, Canada.

出版信息

Surg Obes Relat Dis. 2006 Nov-Dec;2(6):587-91. doi: 10.1016/j.soard.2006.08.006. Epub 2006 Sep 22.

Abstract

BACKGROUND

Obesity is currently recognized as a global epidemic. According to recent statistics, the prevalence of obesity increased from 13.8% of the Canadian population in 1978-1979 to 23.1% in 2004, and the prevalence of morbid obesity increased from .9% in 1978-1979 to 2.7% in 2004. Obesity is a known risk factor for highly prevalent chronic diseases, including cardiovascular and musculoskeletal disorders. The objective of the study was to assess the impact of bariatric surgery on cardiovascular and musculoskeletal morbidity.

METHODS

This was an observational study that compared a cohort of 1035 morbidly obese patients treated with bariatric surgery at the Centre for Bariatric Surgery, McGill University Health Centre with a matched cohort of 5746 morbidly obese nonsurgically treated controls. Data were obtained from the Quebec provincial health insurance database (Régie de l'Assurance Maladie du Québec). Morbidity indicators included diagnoses or treatment for cardiovascular or musculoskeletal disorders.

RESULTS

Patients who underwent bariatric surgery had a significant 62% mean reduction in excess weight and 32% mean reduction in body mass index (P < .001). Compared with the matched controls, patients who had undergone bariatric surgery had significantly lower rates of diagnoses and treatments related to cardiovascular and musculoskeletal conditions.

CONCLUSIONS

These results indicate that bariatric surgery is effective in reducing weight and significantly reduces the risk of cardiovascular and musculoskeletal morbidity.

摘要

背景

肥胖目前被视为一种全球流行病。根据最近的统计数据,肥胖症的患病率从1978 - 1979年加拿大人口的13.8%上升到2004年的23.1%,而病态肥胖症的患病率从1978 - 1979年的0.9%上升到2004年的2.7%。肥胖是包括心血管和肌肉骨骼疾病在内的高度流行的慢性疾病的已知风险因素。本研究的目的是评估减肥手术对心血管和肌肉骨骼疾病发病率的影响。

方法

这是一项观察性研究,将麦吉尔大学健康中心减肥手术中心接受减肥手术的1035例病态肥胖患者队列与5746例未接受手术治疗的病态肥胖对照匹配队列进行比较。数据来自魁北克省医疗保险数据库(魁北克医疗保险局)。发病率指标包括心血管或肌肉骨骼疾病的诊断或治疗。

结果

接受减肥手术的患者平均超重显著降低62%,体重指数平均降低32%(P < 0.001)。与匹配的对照组相比,接受减肥手术的患者与心血管和肌肉骨骼疾病相关的诊断和治疗率显著较低。

结论

这些结果表明,减肥手术在减轻体重方面有效,并显著降低心血管和肌肉骨骼疾病的发病风险。

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