Petti Stefano, Scully Crispian
Department of Public Health Sciences G. Sanarelli, University La Sapienza, Rome, Italy.
Oral Oncol. 2007 Apr;43(4):408-15. doi: 10.1016/j.oraloncology.2006.04.010. Epub 2006 Sep 25.
Information leaflets can be stored and read several times at the patient's own convenience and speed and, therefore, might contribute to increasing the long-term oral cancer knowledge and awareness. This hypothesis was investigated in a sample of adults living in a small central Italian town. The two groups of patients selected (Intervention, 100 subjects; Control, 84 subjects) were all aged 40 years and had never received oral cancer counselling or examination previously. Subjects completed a questionnaire (PRE) containing items regarding oral cancer epidemiology and prevention. Thereafter, the Intervention patients received the oral cancer information leaflet. One year later, patients from both groups were re-contacted and most (97 Intervention, 79 Control subjects, overall participation rate, 95.7%) completed the same questionnaire (POST). The POST questionnaire score, the score increment and the proportion of patients who sought an oral cancer examination during the year follow-up were used as markers of long-term knowledge, knowledge improvement and awareness, respectively. The between group differences in mean PRE score, POST score, score increment and proportion of subjects who had an examination were assessed by conventional statistical tests. The effect of leaflet corrected for confounders also was assessed using multiple regression analyses. No difference in PRE score and awareness was found. However, the mean POST score and the score increment were significantly higher in the Intervention group. The leaflet significantly increased knowledge but not awareness, with statistically significant effects from high educational level and younger age. It is concluded that the information leaflet had a significant effect in raising the long-term oral cancer knowledge in the general public. It also had a secondary effect on disease awareness in the locale.
信息手册可以由患者根据自身方便程度和速度进行多次存储和阅读，因此，可能有助于提高长期的口腔癌知识和意识。在意大利中部一个小镇生活的成年人样本中对这一假设进行了调查。所选取的两组患者（干预组，100名受试者；对照组，84名受试者）均为40岁，且此前从未接受过口腔癌咨询或检查。受试者完成了一份包含口腔癌流行病学和预防相关项目的问卷（PRE）。此后，干预组患者收到了口腔癌信息手册。一年后，再次联系两组患者，大多数（干预组97名，对照组79名受试者，总体参与率95.7%）完成了相同的问卷（POST）。POST问卷得分、得分增量以及在一年随访期间寻求口腔癌检查的患者比例分别用作长期知识、知识改善和意识的指标。通过常规统计检验评估两组在PRE平均得分、POST得分、得分增量以及进行检查的受试者比例方面的差异。还使用多元回归分析评估了校正混杂因素后的手册效果。在PRE得分和意识方面未发现差异。然而，干预组的POST平均得分和得分增量显著更高。该手册显著增加了知识，但未提高意识，在高教育水平和年轻患者中具有统计学显著效果。得出的结论是，信息手册在提高普通公众的长期口腔癌知识方面具有显著效果。它对当地的疾病意识也有次要影响。
