López-Candales Angel, Rajagopalan Navin, Saxena Neil, Gulyasy Beth, Edelman Kathy, Bazaz Raveen
Cardiovascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Am J Cardiol. 2006 Oct 1;98(7):973-7. doi: 10.1016/j.amjcard.2006.04.041. Epub 2006 Aug 17.
Maximal tricuspid annular plane systolic excursion (TAPSE) correlates well with right ventricular (RV) function; however, little is known regarding the impact of left ventricular (LV) systolic function on TAPSE. Consequently, TAPSE was examined in 206 patients (105 men; mean age 56 +/- 17 years), and the data were analyzed with respect to RV (RV fractional area change 45 +/- 19%) and LV (56 +/- 17%) systolic function. The mean TAPSE for the population studied was 1.97 +/- 0.72 cm. Although a strong linear correlation was noted between RV fractional area change and TAPSE (r = 0.73, p <0.0001), relative differences with regard to TAPSE were also found. First, the greatest TAPSE was noted only when RV and LV systolic function were normal (2.46 +/- 0.50 cm). Second, patients with reduced RV systolic function had the smallest TAPSE (1.28 +/- 0.48 cm, p <0.0001). Third, patients with normal RV function but reduced LV systolic function had TAPSE (1.91 +/- 0.54 cm, p <0.0001) that was intermediate between that of patients with normal RV and LV systolic function and those with abnormal RV systolic function. Fourth, patients with reduced biventricular function had the smallest TAPSE (1.16 +/- 0.41 cm, p <0.0001). In conclusion, TAPSE is not only determined by RV systolic function but also appears to depend on LV systolic function. TAPSE <2.0 cm is associated with some degree of either RV or LV dysfunction, whereas a value >2.0 cm suggests normal biventricular systolic function.
三尖瓣环平面收缩期最大位移(TAPSE)与右心室(RV)功能密切相关;然而,关于左心室(LV)收缩功能对TAPSE的影响却知之甚少。因此,对206例患者(105例男性;平均年龄56±17岁)进行了TAPSE检查,并根据RV(RV面积变化分数45±19%)和LV(56±17%)收缩功能对数据进行了分析。所研究人群的平均TAPSE为1.97±0.72 cm。虽然RV面积变化分数与TAPSE之间存在很强的线性相关性(r = 0.73,p <0.0001),但也发现了TAPSE的相对差异。首先,仅当RV和LV收缩功能正常时,TAPSE最大(2.46±0.50 cm)。其次,RV收缩功能降低的患者TAPSE最小(1.28±0.48 cm,p <0.0001)。第三,RV功能正常但LV收缩功能降低的患者TAPSE(1.91±0.54 cm,p <0.0001)介于RV和LV收缩功能正常的患者与RV收缩功能异常的患者之间。第四,双心室功能降低的患者TAPSE最小(1.16±0.41 cm,p <0.0001)。总之,TAPSE不仅取决于RV收缩功能,似乎还取决于LV收缩功能。TAPSE<2.0 cm与RV或LV的某种程度功能障碍相关,而>2.0 cm的值提示双心室收缩功能正常。