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东非狒狒(豚尾狒狒)的正常生化值。

Normal biochemistry values in baboons (Papio C. cinocephalus).

作者信息

Cano M J, Desco M, Garcia-Barreno P

机构信息

Departamento de Medicina y Cirugía Experimental, Hospital General Gregorio Marañón, Madrid, Spain.

出版信息

Comp Biochem Physiol B. 1990;96(4):647-9. doi: 10.1016/0305-0491(90)90208-b.

Abstract
  1. Analysis of biochemical parameters was carried out on material pooled from 10 baboons, adult male and female, of the Papio c. cinocephalus strain. 2. The values determined were for the common metabolites and enzymes utilized for specific studies in general metabolism (urea, glucose, cholesterol, phospholipids, bilirubin, uric acid, creatinine, alkaline phosphatase, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, lactic dehydrogenase, leucine amino peptidase, gamma glutamyl transpeptidase, total creatine kinase and amylase). Total protein and its fractions (ratio albumin/globulin, albumin, alpha 1-globulin and alpha 2-globulin) were also determined. 3. Results of these studies were compared with values for normal human adults. 4. The differences obtained between the respective ranges can be explained by the different physiology of the two species and, possibly, may also be caused by the use of human substrates in the enzyme assays. 5. Through the determination of normal values for the baboon, this study provides values for this species as an experimental animal in biomedical research.
摘要
  1. 对来自10只成年雄性和雌性豚尾狒狒(Papio c. cinocephalus品系)的混合材料进行了生化参数分析。2. 所测定的值是用于一般代谢特定研究的常见代谢物和酶(尿素、葡萄糖、胆固醇、磷脂、胆红素、尿酸、肌酐、碱性磷酸酶、谷草转氨酶、谷丙转氨酶、乳酸脱氢酶、亮氨酸氨肽酶、γ-谷氨酰转肽酶、总肌酸激酶和淀粉酶)。还测定了总蛋白及其组分(白蛋白/球蛋白比值、白蛋白、α1-球蛋白和α2-球蛋白)。3. 将这些研究结果与正常成年人的值进行了比较。4. 各自范围之间获得的差异可以通过两个物种不同的生理学来解释,并且可能也由酶测定中使用人类底物引起。5. 通过测定狒狒的正常值,本研究为该物种作为生物医学研究中的实验动物提供了数值。

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